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Biological Monitoring of O‐toluidine in Urine Pretreated by an Enzymatic Deconjugation Method

Journal of occupational health(2019)

引用 4|浏览19
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摘要
To establish an enzymatic deconjugation method to separately quantify urinary o‐toluidine (OT), its six metabolites, another six chemicals present in an OT‐processing plant, and one metabolite of p‐toluidine, and to propose optimal urinary biological monitoring items of OT exposure.
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关键词
biological monitoring,high pressure liquid chromatography,hydrolysis,o-Toluidine,tandem mass spectrometry,beta-Glucuronidase/arylsulfatase
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