Imaging features of triple-negative breast cancers according to androgen receptor status.

European Journal of Radiology(2019)

引用 15|浏览62
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摘要
•TNBC is a heterogeneous collection of breast cancers that is defined by the lack of ER, PR and HER-2 expression.•The luminal androgen receptor (LAR) subtype of TNBC is associated with lower rates of pathologic complete response.•Androgen receptor (AR) status is a surrogate immunohistochemical marker for the LAR subtype of TNBC.•Imaging surrogates of the chemoresistant LAR subtype could also be potentially identified.•AR+ TNBC significantly associates with masses with high density, calcifications, and irregular shape.
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关键词
AR,AR+,AR–,HER2,IHC,LAR,MRI,NAST,pCR,TNBC
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