Monodisperse Polysarcosine-Based Highly-Loaded Antibody-Drug Conjugates

Warren Viricel,Guy Fournet,Sabine Beaumel,Emeline Perrial,Sebastien Papot,Charles Dumontet,Benoit Joseph

Chemical science（2019）

引用 54|浏览31

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摘要

A new antibody-drug conjugate (ADC) chemical drug-linker platform based on polysarcosine enables increased drug-loading, improved pharmacokinetics and exquisite in vivo potency.

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