Modelling the development of anthelmintic resistance in cyathostomin parasites: The importance of genetic and fitness parameters.

•A model for the complete cyathostomin lifecycle was constructed.•Multiple mechanisms for the genetics of anthelmintic resistance were incorporated.•Treatment strategies were compared for development of anthelmintic resistance.•The genetics of resistance had a large effect on the rate at which resistance developed.•Different strategies had similar relative ranking regardless of genetic mechanism assumed.