Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Adam M Staffaroni,Lynn Bajorek,Kaitlin B Casaletto,Yann Cobigo,Sheng-Yang M Goh,Amy Wolf,Hilary W Heuer,Fanny M Elahi,Peter A Ljubenkov,Reilly Dever,John Kornak,Brian Appleby,Jessica Bove,Yvette Bordelon,Patrick Brannelly,Danielle Brushaber,Christina Caso,Giovanni Coppola,Christina Dheel,Bradford C Dickerson,Susan Dickinson, Sophia Dominguez,Kimiko Domoto-Reilly, Kelly Faber, Jessica Ferrall,Julie A Fields, Ann Fishman,Jamie Fong,Tatiana Foroud,Leah K Forsberg,Ralitza Gavrilova,Debra Gearhart, Behnaz Ghazanfari,Nupur Ghoshal,Jill Goldman,Jonathan Graff-Radford,Neill Graff-Radford,Ian Grant,Murray Grossman,Dana Haley,Ging-Yuek Hsiung,Edward D Huey,David J Irwin,David T Jones, Lynne Jones,Kejal Kantarci,Anna Karydas, Daniel I Kaufer,Diana R Kerwin,David S Knopman,Ruth Kraft,Walter K Kremers,Walter A Kukull,Irene Litvan,Diane Lucente,Codrin Lungu,Ian R Mackenzie, Miranda Maldonado,Masood Manoochehri,Scott M McGinnis,Emily McKinley,Mario F Mendez,Bruce L Miller,Namita Multani,Chiadi Onyike,Jaya Padmanabhan, Alex Pantelyat, Rodney Pearlman, Len Petrucelli,Madeline Potter, Rosa Rademakers,Eliana Marisa Ramos,Katherine P Rankin,Katya Rascovsky,Erik D Roberson,Emily Rogalski, Pheth Sengdy,Leslie M Shaw,Jeremy Syrjanen, M Carmela Tartaglia,Nadine Tatton,Joanne Taylor,Arthur Toga,John Q Trojanowski,Sandra Weintraub,Ping Wang,Bonnie Wong,Zbigniew Wszolek,Adam L Boxer,Brad F Boeve,Joel H Kramer,Howard J Rosen

Alzheimer's & dementia : the journal of the Alzheimer's Association（2019）

引用 32|浏览29

暂无评分

摘要

The NIH-EXAMINER is sensitive to cognitive changes in presymptomatic familial FTLD and is a promising surrogate endpoint.

查看译文

关键词

Behavioral variant,Cognition,Corticobasal syndrome,Fluency,Genetic,Inhibition,Neuropsychology,Nonfluent variant,Primary progressive aphasia,Progranulin,Progressive supranuclear palsy,Semantic variant,Set-shifting,Tau,Working memory

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要