Dynamic Functional Connectivity Analysis of Functional MRI Based on Copula Time-Varying Correlation.

FMRI data of 138 human participants watching a Pixar animated movie were analyzed by the proposed method based on five a priori selected brain regions in the cortex. Based on statistical group analysis results, it was discovered that (1) the correlation between the left temporoparietal junction (LTPJ) and the primary visual cortex (V1) and the correlation between the dorsal posterior cingulate cortex (dPCC) and V1 were significantly higher for older age groups (5yo-Adult) more often than for younger age groups (3yo-4yo), and (2) the right temporoparietal junction (RTPJ), LTPJ, and dPCC were significantly correlated in all age groups at most of the scanning time periods.