Comparative assessment of chewing gum and ibuprofen in the management of orthodontic pain with fixed appliances: A pragmatic multicenter randomized controlled trial.

American Journal of Orthodontics and Dentofacial Orthopedics(2016)

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摘要
•Chewing sugar-free gum might help orthodontic patients to use less ibuprofen.•Chewing sugar-free gum had no statistically significant effect on bond failures.
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