Clomiphene citrate treatment outcomes in Taiwanese hypogonadal men: A single-center preliminary report☆

Objective: We evaluated the treatment efficacy of clomiphene citrate (CC) in hypogonadal men. Methods: We retrospectively reviewed our patients with a diagnosis of hypogonadism who received CC treatment, and compared the pretreatment and post- treatment serum testosterone levels. Subjective patient improvements were recorded using the Androgen Deficiency in Aging Males questionnaire. Results: A total of 10 patients were included in our analysis. Mean serum testosterone level increase from 246 +/- 76 ng/dL to 548 +/- 281 ng/dL was noted after treatment (p < 0.01). Eight (80%) patients successfully reached a target serum testosterone level of > 400 ng/dL after treatment. Conclusion: CC is an effective alternative treatment for patients with hypogonadism. Copyright (C) 2016, Taiwan Urological Association. Published by Elsevier Taiwan LLC.