Ganzkörperkryotherapie bei Patienten mit entzündlich-rheumatischen Erkrankungen : Eine prospektive Studie (ORIGINALARBEIT)

Medizinische Klinik(2009)

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摘要
Background:As yet, whole-body cryotherapy is especially used for the therapy of chronic inflammatory arthritis. An analgetic effect has been described in several studies. However, only few data exist concerning the long-term effects of this therapy.Patients and Methods:A total of 60 patients with rheumatoid arthritis (n = 48), and ankylosing spondylitis (n = 12) was analyzed. Patients underwent treatment with whole-body cryotherapy twice a day. The average age was 55.7 ± 10.33. The study group consisted of 48 female and twelve male patients. The average number of therapeutic treatments with cryotherapy was 15.8 ± 8.37, the average follow-up 63.4 ± 63.48 days.Results:13 patients (21.7%) discontinued treatment because of adverse effects. For patients with rheumatoid arthritis, DAS28 (Disease Activity Score) and VAS (visual analog scale) were determined. A significant reduction of both parameters was found (DAS 3.9 ± 1.22 vs. 3.4 ± 1.08; p < 0.01; VAS 51.4 ± 16.62 vs. 37.9 ± 19.13; p < 0.01). BASDAI (Bath Ankylosing Spondylitis Disease Activity Index) was analyzed for patients with ankylosing spondylitis, and also showed a significant reduction (4.4 ± 1.91 vs. 3.1 ± 1.34; p = 0.01).Conclusion:Thus, whole-body cryotherapy is an effective option in the concept of treatment of inflammatory rheumatic diseases. The relief of pain allows an intensification of physiotherapy. A significant reduction of pain over a period of 2 months could be shown.
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