Effects of Concurrent Training in People Living with Hiv/Aids: A Randomized Clinical Trial

PURPOSE: To evaluate the effects of 16 weeks of concurrent training on body composition, immunological and respiratory variables in people living with HIV/AIDS undergoing highly active antiretroviral therapy (HAART). METHODS: The procedures followed the rules for Randomized Clinical Trials described by CONSORT statement for non-pharmacological treatments. The sample consisted of 58 HIV-positive volunteers undergoing HAART, which were randomized and assigned into two experimental groups: 1. Control (C) and 2. Concurrent Training (T). The T group performed 16 weeks of aerobic and strength exercise training (concurrent training), 3 times a week. The C group performed stretching and recreational activities. Body composition was measured by Dual-Energy X-Ray Absorptiometry, 12-h fasting serum interleukins (IL-4, 5, 6, 8, 10, IFN-, GM-CSF, e TNF) determined by Multiplex Assay (Luminex), maximum O2 uptake (VO2max) consumption determined by gas analysis (MetaLyzer 3B), and peak running speed (Vpeak) assessed during incremental treadmill tests. RESULTS: T group showed the following modifications on body composition: reduction of 6% on fat mass, 8% on trunk fat mass, 10% of android fat, and 9% on total fat mass (p<0.05). From all cytokines analyzed only IL-8 levels were lower in T group (p<0.05) when compared to C group. Finally, VO2max and Vpeak increased 21.5% and 17.5% in T group in comparison to C group, respectively (p<0.05). CONCLUSION: Concurrent training provided benefits in body composition, immunological and respiratory parameters in people living with HIV/AIDS undergoing HAART.