The Catalyst‐Controlled Divergent Cascade Reactions of Homo‐Propargylic Amines and Nitrones: Synthesis of Pyrrolo‐Isoxazolidines and γ‐Lactams

Two controllable one‐pot cascade cyclization reactions of homopropargylic amines and nitrones were developed by using different metal Cu and Ag salts. The pyrroloisoxazolidines and γ‐lactams were obtained in good to high yields, respectively. Herein, nitrones played dual roles, both as 1,3‐dipoles and oxidants, and four stereocenters were simultaneously formed in the hydroamination cyclization‐1,3‐dipolar cycloaddition cascade reaction of homopropargylic amines and nitrones in the presence of AgOAc.