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Core–shell-type polymer–lipid nanoparticles for the transdermal delivery of daidzein

Zaitongguli Wusiman,Liang Sun,Tiantian Zuo,Yunzhi Yin,Xiaoming Yang,Qi Shen

Micro & Nano Letters（2018）

Cited 3|Views7
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Abstract
Daidzein (DZ) is an ideal Chinese herb for treating cardiocerebrovascular disease. Despite its poor water solubility and limited application, DZ was successfully loaded, along with penetration enhancer azone, onto core–shell-type polymer–lipid nanoparticles through a two-step preparation method. The mean particle diameter, encapsulation efficiency, and drug-loading rate of DZ–polymer-azone–lipid n...
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Key words
nanoparticles,drugs,skin,particle size,encapsulation,drug delivery systems,polymers,nanomedicine,diseases,optical microscopy
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