Coupled fermentation-bioconversion process for production of chiral α-chlorohydrin with recombinant ketoreductase

Zhongyi Yang, Xin Li, Ganghua Cai, Chunlong Peng,Yongjun Zhong,Xi Luo

Process Biochemistry（2019）

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摘要

•Coupled fermentation-bioconversion process for the production of α-chlorohydrin.•High temperature fermentation process for the release of intracellular ketoreductase.•Conversion of 200 g/L α-chloroketone in heterogeneous reaction mixture and reuse of the enzyme.

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关键词

α-chlorohydrin,Ketoreductase,Coupled fermentation-bioconversion process,Heterogeneous reaction,Reuse

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