Oxidative β-Halogenation of Alcohols: A Concise and Diastereoselective Approach to Halohydrins

beta-Halohydrins bearing transformable halo- and hydroxyl groups, are easily converted into various valuable blocks in organic and pharmaceutical synthesis. A diastereoselective -halogenation of benzylic alcohols was achieved under simple and low-cost conditions, which provided a direct synthesis of -halohydrins. The simple reaction conditions, easily available reagents, high diastereoselectivities, and additional oxidant-free make this reaction very attractive and practical.