Coronary computed tomography angiography and predictive factors of coronary events in patients with non-valvular atrial fibrillation

Background Clinical scores of thromboembolism risk (CHA2DS2-VASc) and hemorrhagic risk (HAS-BLED) have been developed to characterize the patients with non-valvular atrial fibrillation. These scores have been defined in part with clinical risk factors of atherosclerosis. Before their ablation, a coronary computed tomography angiography enables to determine the Agatston calcium score (coronary artery calcium score) which is a atherosclerosis marker. Purpose In this study, tried to find out a link between the Agatston calcium score and the CHA2DS2-VASc, as well as between the Agatston calcium score and the HAS-BLED. Methods Three hundred and forty-four atrial fibrillation subjects were included in our observational and retrospective study between January 1st, 2013 and January 1st, 2017, in the same institute. All of these patients had undergone a coronary computed tomography angiography. Results Three hundred and seventeen patients were included in this study: 233 men (73.5%) and 84 women (26.5%), with an average age of 60,4 years. Agatston calcium score was significantly higher in the subjects with CHA2DS2-VASc score ≥ 2 ( P P P  = 0.03 for CHA2DS2-VASc ≥ 3) ( Table 1 ). This link is also found between the Agatston calcium score and the HAS-BLED score ≥ 2 ( P Conclusion This study shows a strong link between the atherosclerosis marker determined by CT (coronary artery calcium score), the thrombo-embolism risk score (CHA2DS2-VASc) and the hemorrhagic risk score (HAS-BLED) determined by clinical elements in patients with non-valvular atrial fibrillation.