Mesenchymal stem cells reduce ER stress via PERK-Nrf2 pathway in aged mouse model
EUROPEAN RESPIRATORY JOURNAL(2019)
摘要
Our data suggest that MSC operate on ER stress via several pathways, but the PERK-Nrf2 pathway revealed to be the main functioning pathway in our bleomycin model.
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关键词
ageing,cell therapy,endoplasmic reticulum stress,lung fibrosis,mesenchymal stem cell
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