A systematic review: Impact of endocrine disrupting chemicals exposure on fecundity as measured by time to pregnancy

Environmental Research(2019)

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摘要
•Studies examining the relationship between the selected EDCs exposure – Brominated flame retardants, Phthalates or Organophosphates flame retardants and human fecundity as measured by time to pregnancy were limited in number (14 studies).•Evidence from this review was suggestive of a link between PBDE exposure and increased time to pregnancy. Evidence also exists on phthalates exposure and increased or decreased TTP. However, causal association between the EDCs and fecundity was difficult establish due to inconsistency of results, and insufficient number of studies included.•As this review found ‘weak associations between exposure to selected EDCs and fecundity as measured by TTP’, studies focusing on policies aimed to exposure prevention should be urgently required.
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EDCs,BFR,HBCD,PBDE,TBBPA,POPs,OPFRs,phthalates: MnBP,MBzP,MMP,MEP,MCHP,MiNP,MCP,MEHP,MEOHP,IVF,DE,PRISMA,OR,NOS,WCRF,BMI,FR,CI,SD
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