Abstract TP552: Race and Gender Differences in Mortality Due to Spontaneous Subarachnoid Hemorrhage

Background and Aims: Spontaneous subarachnoid hemorrhage (sSAH) is a rare stroke event with a relatively high rate of mortality. There are a number of risk factors, including gender and race, for sSAH. However, it is unclear whether these risk factors are associated with the age of mortality due to sSAH. Methods: We utilized the CDC Wonder dataset (wonder.cdc.gov) “Underlying Cause of Mortality 1999-2016” to query for sSAH mortality in named arterial distributions. Age, race and other demographic data from the entire United States was available. Statistical differences between populations of different races including Caucasian African American, Asian, or Native American or between genders were assessed using a Chi-squared test of independence and unpaired Student’s t tests. Results: Our analysis detected an association between race and age range of mortality due to sSAH (χ 2 = 414.00, df = 51, p -value = 1.6E-58). Further analyses revealed a younger age of mortality due to sSAH in males as compared to females, with an average age of mortality at 53.3 and 60.0 years old respectively ( p < 0.0001). Notably, race differences were greater in females than in males, whereby black females exhibited the youngest age of mortality due to sSAH with an average age of mortality at 51.8 years as compared to 61.6 for non-black females ( p < 0.0001). Conclusion: These findings suggest that underlying differences in race and gender have an effect on age of mortality due to sSAH.