Cerebellar low-intensity focused ultrasound stimulation can normalize asymmetrical hemispheric delta power after mouse ischemic stroke

Introduction: Functional asymmetry between lesioned and non-lesioned hemispheres after unilateral middle cerebral artery (MCA) stroke could be indicative of cerebral pathophysiology. We propose a low-intensity focused ultrasound (LIFU) can non-invasively stimulate the deep cerebellar nuclei and induce plasticity for reestablishing the balance between two cerebral hemispheres.