Enantioselective Alkynylation of Isatin Derivatives Using a Chiral Phase-Transfer/Transition-Metal Hybrid Catalyst System

ACS Catalysis（2019）

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摘要

An enantioselective alkynylation of isatin derivatives can be realized by using a hybrid catalyst system consisting of chiral phase-transfer catalyst and transition-metal catalyst. The chiral alkynylation products can be used as versatile intermediates for further synthetic transformations.

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关键词

phase-transfer catalyst,hybrid catalyst,asymmetric alkynylation,isatin,silver acetate

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