A Hyaluronan/Methylcellulose-Based Hydrogel for Local Cell and Biomolecule Delivery to the Central Nervous System

•Delivery of biomolecules and cells to the CNS remains a challenge.•Hyaluronan/methylcellulose (HAMC) hydrogel promotes cell survival in vivo.•HAMC is a versatile delivery vehicle for controlled biomolecule delivery directly to CNS tissue.•Efficacy of HAMC can be seen in models of retinal degeneration, stroke, and spinal cord injury.