Investigation of CCR5-Δ32 (rs333) genetic polymorphism frequency and its relationship with HIV-1 susceptibility and disease progression: A Moroccan case-control study

Fatima Zahra Farissi,Hicham El Annaz,Moulay Abdelaziz El Alaoui,Safae Elkochri,Mohamed Reda Tagajdid,Rachid Abi,Sanaa Alaoui Amine,Najwa Alaoui,Jalal Kasouati,Nadia Touil,Rachid Frikh,Naoufal Hjira,El Mostapha El Fahime,Saad Mrani

Gene Reports（2019）

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摘要

•CCR5-Δ32 (rs333) polymorphism exists among HIV-1 seropositive Moroccan patients.•Susceptibility to HIV-1 infection is probably not affected by CCR5-Δ32 mutation in Moroccans.•No significant association was detected between WT/Δ32 genotype and HIV-1 disease progression.

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关键词

ART,CCL,CCR5,CCR2,CDC,CXCR-4,ELISA,HAART,HWE,IQR,SDF1,VL,WT,Δ32

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