Abstract 151: Therapeutic Intensity in Medically Managed Incident Heart Failure Patients with and without Mitral Regurgitation: A Claims Based Analysis

Background: Understanding the therapeutic intensity of medically managed heart failure (HF) patients with and without secondary MR can be challenging when using claims data. This research showcases the development of a therapeutic intensity score (TIS) and reports the impact of the score on annual all-cause inpatient hospitalizations. Methods: This study included data from the Truven Health MarketScan Commercial Claims and Medicare Supplemental Databases from October 2011 to September 2016. Inclusion criteria were patients who had a minimum of 1 inpatient or 2 outpatient claims for HF with a 6-month pre-period (baseline). A 6-month post-period (landmark) after HF index was used to capture MR diagnosis and severity. Following the landmark period, patients were required to have 12 months of continuous medical and prescription drug plan enrollment with at least two records of HF medication refills. Additional exclusions (age under 18, chordal rupture, hospice, etc) were applied. TIS was calculated based on t...