Ni-thiosaccharinate complexes: Synthesis, characterization and DFT studies. Biological properties as superoxide dismutase mimetics and as anti-carcinogenic agents

Fermín Delgado, Eva Nicova,Mariela Agotegaray,Verónica González Pardo,Viviana Dorn,Robert A. Burrow,Mariana Dennehy

Inorganica Chimica Acta（2019）

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摘要

•Two nickel thiosaccharinate complexes were synthesized.•Their single crystal X-ray structures are reported.•The complexes show moderate SOD mimic activity.•The complexes triggered cell proliferation inhibition for Kaposi’s sarcoma.

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关键词

Nickel,Thiones,Phosphane,Crystalline structure,Superoxide dismutase mimetic activity,Cell proliferation inhibition

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