MIF Promoter Polymorphisms Are Associated with Epiretinal Membrane but Not Retinal Detachment with PVR in an American Population.
Experimental eye research（2019）
摘要
• MIF promoter polymorphisms rs5844572 and rs755622 are implicated in many inflammatory conditions. • Case-cohort genetic association study in the US from 2012 to 2018. • 601 study subjects: RD (n = 180), RD with PVR (n = 120), ERM (n = 100) and 201 controls. • Significant association of rs755622 (C/C) and homozygous C7 haplotype with ERM. • No association was found between RD or PVR and the MIF polymorphisms.
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