Persistent Organic Pollutants and the Incidence of Type 2 Diabetes in the CARLA and KORA Cohort Studies.

Kathrin Wolf,Brenda W.C. Bongaerts,Alexandra Schneider,Cornelia Huth,Christa Meisinger,Annette Peters,Andrea Schneider,Jürgen Wittsiepe,Karl-Werner Schramm,Karin Halina Greiser,Saskia Hartwig,Alexander Kluttig,Wolfgang Rathmann

Environment International（2019）

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摘要

•Longitudinal studies on the association between POPs and diabetes in the general population are scarce.•We investigated 132 incident cases of type 2 diabetes and 264 age- and sex-matched controls.•Internal exposure to 3 polychlorinated biphenyls and 3 pesticides was determined at baseline.•PCB-138 and PCB-153 were positively associated with incident type 2 diabetes.•Women and non-obese participants indicated higher OR.

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关键词

Type 2 diabetes,Incidence,Environmental contaminates,Case-control study,Epidemiology

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