Aldehyde dehydrogenase isoforms and inflammatory cell populations are differentially expressed in term human placentas affected by intrauterine growth restriction

Alison Chu, Parisa Najafzadeh,Peggy Sullivan,Brian Cone, Ryan Elshimali,Hania Shakeri,Carla Janzen,Vei Mah,Madhuri Wadehra

Placenta（2019）

引用 11|浏览12

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摘要

•Macrophages in the placenta skew towards a pro-inflammatory state in IUGR.•Aldehyde dehydrogenases are expressed in distinct placental cell populations.•ALDH isoforms trend to have higher expression in specific cell populations in IUGR.

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关键词

Aldehyde dehydrogenase (ALDH),Placenta,Oxidative stress,Intrauterine growth restriction,Placental insufficiency,Macrophage polarization

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