Molecular identification of grouper Igfbp1 and its mRNA expression in primary hepatocytes under Gh and Insulin.

Guokun Yang, Beichen Chen,Caiyun Sun,Xi Yuan,Yazhou Zhang,Jingkai Qin,Wensheng Li

General and Comparative Endocrinology（2019）

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摘要

•igfbp1 was cloned and characterized in grouper.•igfbp1 mRNA was highly expressed in liver and brain regions in grouper.•igfbp1 mRNA expression in grouper liver was regulated by nutritional status.•igfbp1 mRNA expression was suppressed by Gh or Insulin in primary grouper hepatocytes.

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关键词

IGF,IGFBPs,UTR,ORF,Gh/GH,IGFR,ALS,RGD,cAMP,PCR,RACE,RT-PCR,FBS,IRE

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