High-dose trimethoprim-sulfamethoxazole and clindamycin for Staphylococcus aureus endocarditis

Hervé Tissot-Dupont,Frédérique Gouriet,Leopold Oliver,Matthieu Jamme,Jean-Paul Casalta,Marie-Thérèse Jimeno,Florent Arregle,Cécile Lavoute,Sandrine Hubert,Mary Philip,Hélène Martel,Alberto Riberi,Gilbert Habib,Didier Raoult

International Journal of Antimicrobial Agents（2019）

引用 29|浏览26

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摘要

•Staphylococcus aureus infective endocarditis can be treated with oral trimethoprim-sulfamethoxazole +/− clindamycin.•A rapid switch to oral treatment reduces the length of hospital stay.•A rapid switch to oral treatment reduces the mortality rate of S. aureus endocarditis.

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关键词

Endocarditis,Staphylococcus aureus,Oral route,Trimethoprim-sulfamethoxazole,Clindamycin,Mortality

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