CXCR4 in human osteosarcoma malignant progression. The response of osteosarcoma cell lines to the fully human CXCR4 antibody MDX1338.

Journal of Bone Oncology（2019）

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摘要

Osteosarcoma (OS) is the most frequent primary malignant tumour of bone and metastases occur in 30% of cases, the 5-year survival rate is 25–30%.

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关键词

Sarcoma,Metastasis,CXCR4 antagonists,Prognosis,Biomarkers

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