Complementary techniques (spICP-MS, TEM, and HPLC-ICP-MS) reveal the degradation of 40 nm citrate-stabilized Au nanoparticles in rat liver after intraperitoneal injection

Roberto Álvarez-Fernández García,Nerea Fernández-Iglesias,Carlos López-Chaves,Cristina Sánchez-González,J. Llopis,Maria Montes-Bayón,Jörg Bettmer

Journal of Trace Elements in Medicine and Biology（2019）

引用 16|浏览23

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摘要

•Studies on the degradation of Au nanoparticles in rat liver after intraperitoneal injection.•Liver extracts analysed by TEM, spICP-MS and HPLC-ICP-MS.•Smaller Au nanoparticles and low-molecular Au species could be detected.

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关键词

Gold nanoparticles,Single particle ICP-MS,HPLC-ICP-MS,TEM,Rat liver tissues

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