Whole Cell Analysis Ranging from Intercellular Assay to Organ on a Chip

Current treatments and diagnostic devices will be efficient and successful given that the knowledge of cell and tissue is well known. To understand the sub-micron to macro world that is contained in a cell or tissue on a functional and structural level, a comprehensive method is necessary for not only measurement of physiological parameters but also of its molecular interactions, protein bindings and membrane changes that happen during a natural or stimulus induced phenomena. Several groups have introduced techniques in several areas for measuring of the smallest scale of a biological system, the cell, to organ on chip devices that replicate a small portion of a full organ. In this review, we have categorized those methods based on scale and application and reviewed several views that'll give an overall understanding of current available techniques for such application.