The antitrypanosomal diarylamidines, diminazene and pentamidine, show anthelmintic activity against Haemonchus contortus in vitro

•We examined the in vitro anthelmintic activity of diarylamidine compounds.•Pentamidine and diminazene inhibited Haemonchus contortus larval development.•Highlights anthelmintic potential of this drug class.•Raises possibility of acid-sensing ion channels as anthelmintic targets.