Canine visceral leishmaniasis biomarkers and their employment in vaccines

Rodolfo Cordeiro Giunchetti,Patricia Silveira,Lucilene Aparecida Resende,Jaqueline Costa Leite,Otoni Alves de Oliveira Melo-Júnior, Marina Luiza Rodrigues- Alves, Laís Moreira Costa,Daniel Ferreira Lair,Vinícius Rossi Chaves,Ingrid dos Santos Soares,Ludmila Zanandreis de Mendonça,Mariana Ferreira Lanna,Helen Silva Ribeiro,Ana Alice Maia-Gonçalves,Thaiza Aline Pereira Santos,Bruno Mendes Roatt,Rodrigo Dian Oliveira Aguiar-Soares,Juliana Vitoriano-Souza,Nádia das Dores Moreira,Fernando Augusto Siqueira Mathias

Veterinary Parasitology（2019）

引用 28|浏览11

暂无评分

摘要

•CD4+/ CD8+ T-cell (proinflammatory profile) is related with a resistance to CVL.•Polyclonal B-cell expansion is associated with high susceptibility in CVL.•IFN-γ and TNF-α are disease resistance related biomarkers.•IL-4, TGF-β and IL-10 are disease susceptibility related biomarkers.

查看译文

关键词

Canine visceral leishmaniasis,Immunopathology,Vaccine,Immunogenicity,Biomarkers

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要