Zn homeostasis in genetic models of Parkinson’s disease in Caenorhabditis elegans

Jessica Baesler,Johannes F. Kopp,Gabriele Pohl,Michael Aschner,Hajo Haase,Tanja Schwerdtle,Julia Bornhorst

Journal of Trace Elements in Medicine and Biology（2019）

引用 12|浏览8

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摘要

•Labile and total Zn quantification as independent markers for zinc status.•Labile Zn quantification in living nematodes by ZinPyr 1.•Age-specific alteration patterns of Zn homeostasis in young and midlife C. elegans.•Altered Zn homeostasis in PD mutants following Zn exposure compared to wildtype worms.

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关键词

Caenorhabditis elegans,Zinc,Zinc homeostasis,Parkinson disease,Labile zinc

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