Location, location, location: nuclear structure regulates gene expression in neurons
Current Opinion in Neurobiology(2019)
摘要
•Nuclear architecture is essential for transcriptional activation in neurons.•Changes in chromosome contacts occur during neuronal differentiation.•Proteins that organize genome loops include cell type specific transcription factors.•Alteration of genome topology is associated with neurological disorders.
更多查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要