Intestinal Inflammation Modulates the Epithelial Response to Butyrate in Patients with Inflammatory Bowel Disease.
Inflammatory bowel diseases(2019)
摘要
Ferrer-Picón et al. show that in active IBD patients, tumor necrosis factor alpha affects the response of the intestinal epithelium to bacteria-derived butyrate. This observation raises questions about the beneficial effects of butyrate supplementation during active inflammation.
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关键词
ulcerative colitis,Crohn's disease,bacterial metabolites,TNF alpha,human organoids
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