Heterogeneous-phase Sonogashira cross-coupling reaction on COC surface for the grafting of biomolecules - Application to isatin.
Colloids and Surfaces B: Biointerfaces(2019)
摘要
•Modification of isatin by Suzuki cross coupling to create original derivatives.•In silico study to evaluate the influence of isatin modification on isatin-AmiC receptor affinity.•Original surface functionalization using Sonogashira cross-coupling.•Surface modification of gold and polymeric surfaces are characterized by different techniques.•Antibacterial adhesion of isatin-device are evaluated.
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关键词
Isatin,Aryldiazonium salts,Biosensors,Surface functionalization,Heterogeneous Sonogashira cross-coupling
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