E2F6-mediated lncRNA CASC2 down-regulation predicts poor prognosis and promotes progression in gastric carcinoma.
Life Sciences(2019)
摘要
Our data demonstrated that E2F6 could regulate the proliferation, invasion and apoptosis of GC cells via inhibiting the expression of CASC2, suggesting that E2F6/CASC2 axis is another regulator of GC progression.
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关键词
Gastric carcinoma,Transcription factor E2F6,Cancer susceptibility candidate 2,Proliferation,Tumorigenesis
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