Disc degeneration induces a mechano-sensitization of disc afferent nerve fibers that associates with low back pain.
Osteoarthritis and Cartilage(2019)
摘要
Our study suggests that enhanced mechano-sensitivity at the afferent nerve fiber innervating degenerated IVD is deeply correlated with LBP development, which supports the hypothesis that hyperexcited responses at the nerve fibers represent a decisive source of LBP.
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关键词
Disc degeneration,Disc afferent nerve fiber,Low back pain,In vivo single nerve recording,Dynamic weight bearing,Morphine
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