Topiramate pharmacokinetics in neonates undergoing therapeutic hypothermia and proposal of an optimized dosing schedule.

Acta paediatrica (Oslo, Norway : 1992)(2020)

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摘要
The dosage schedule of topiramate in these patients should be modified with the aim of decreasing the frequency of seizure events. This article is protected by copyright. All rights reserved.
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hypoxic ischemic encephalopathy,neonates,population pharmacokinetics,therapeutic hypothermia,topiramate dosing
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