A comparison of intravascular and surface cooling devices for targeted temperature management after out-of-hospital cardiac arrest: A nationwide observational study.

This study aimed to compare prognostic difference between intravascular cooling devices (ICDs) and surface cooling devices (SCDs) in targeted temperature management (TTM) recipients. Adult TTM recipients using ICD or SCD during 2012 to 2016 were included in this nationwide observational study. The outcome was survival to hospital discharge and good neurological outcome at hospital discharge. Among 142,905 out-of-hospital cardiac arrest patients, 1159 patients (SCD, n=998; ICD, n=161) were investigated. After propensity score matching for all patients, 161 matched pairs of patients were available for analysis (SCD, n=161; ICD, n=161). We observed no significant differences in the survival to hospital discharge (SCD, n=144 [89.4%] vs ICD, n=150 [93.2%], P=.32) and the good neurological outcomes (SCD, n=86 [53.4%] vs ICD, n=91 [56.5%], P=.65). TTM recipients were categorized by age groups (elderly [age >65 years] vs nonelderly [age <= 65 years]) to compare prognostic difference between ICD and SCD according to the age groups. In the nonelderly group, the use of ICD or SCD was not a significant factor for survival to hospital discharge or good neurologic outcome. Whereas, the use of ICD was significantly associated with good neurological outcome (odds ratio, 3.97; 95% confidence interval, 1.19 - 13.23, P=.02) compared with SCD in the elderly group. There were no significant differences in the survival to hospital discharge and the good neurological outcomes between SCD and ICD recipients. However, the use of ICD might be more beneficial than SCD in elderly patients.