EPO promotes axonal sprouting via upregulating GDF10.

Si-Jia Li,Ke-Fei Cui, Jia-Jia Fu,Xiao-Jie Fu,Yu-Feng Gao,Di Zhang,Zheng-Fang Lu,Yong-Xin Zhang,Lie Yu,Jian-Ping Wang

Neuroscience Letters（2019）

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摘要

•EPO promotes axonal sprouting in a dose-dependent manner.•GDF10 is the executor of EPO-mediated axonal sprouting.•EPO induces GDF10 expression through JAK2-PI3K-NF-κB signaling.

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关键词

EPO,GDF10,NF-κB,p-p65,PI3K,p-PI3K,t-PI3K,JAK2

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