Efficacy of Albumin Treatment for Patients with Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis.

J Fernández,P Angeli,J Trebicka,M Merli,T Gustot,C Alessandria,N K Aagaard,A de Gottardi,T M Welzel, A Gerbes,G Soriano,V Vargas,A Albillos,F Salerno,F Durand,R Bañares,R Stauber, V Prado, M Arteaga, M Hernández-Tejero,F Aziz, F Morando,C Jansen, B Lattanzi,C Moreno,D Campion,H Gronbaek,R Garcia, C Sánchez,E García,A Amorós, M Pavesi, J Clària,R Moreau,V Arroyo

Clinical Gastroenterology and Hepatology（2020）

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摘要

In a randomized trial of patients with advanced cirrhosis and non-SBP infections, in-hospital mortality was similar between those who received albumin plus antibiotics vs those who received only antibiotics (controls). However, patients given albumin were sicker at baseline and, during the follow-up period, a higher proportion had ACLF resolution and a lower proportion had nosocomial infections. ClinicalTrials.gov no: NCT02034279.

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关键词

Acute-on-Chronic Liver Failure,Mortality,Nosocomial Infections,Immune-Modulation

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