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Maturational Phase of Hippocampal Neurogenesis and Cognitive Flexibility.

Ryan D Webler,Sasha Fulton,Tarique D Perera,Jeremy D Coplan

Neuroscience Letters（2019）

Cited 9|Views13
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Abstract
•Number of immature new DG neurons predicts CA3 activity during a cognitive flexibility task.•Higher number of immature new DG neurons and lower CA3 activity are associated with increased cognitive flexibility.•Immature new DG neurons may stifle the retrieval of closely related engrams instantiated in CA3.
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Key words
Hippocampus,Neurogenesis,Cognitive flexibility,BrdU-NeuN,Doublecortin
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