Associations between AR-V7 status in circulating tumour cells, circulating tumour cell count and survival in men with metastatic castration-resistant prostate cancer.

Bodine P S Belderbos,Anieta M Sieuwerts,Esther Oomen-de Hoop,Bianca Mostert,Jaco Kraan,Paul Hamberg,Mai N Van,Corine M Beaufort,Wendy Onstenk,Robert J van Soest,John Martens,Stefan Sleijfer,Ronald de Wit,Ron H J Mathijssen,Martijn P Lolkema

European Journal of Cancer（2019）

引用 21|浏览43

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摘要

•AR-V7 in circulating tumor cells had no additional prognostic value in mCRPC patients.•A predictive biomarker is an important unmet need in prostate cancer treatment.•Prospective trials should investigate if AR-V7 detection may guide treatment selection.

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关键词

AR-V7,Metastatic castration-resistant prostate cancer,Biomarker,Circulating tumour cells

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