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Addition of hydrogen peroxide to methylene blue conjugated to β-cyclodextrin in photodynamic antimicrobial chemotherapy in S. mutans biofilm

Photodiagnosis and Photodynamic Therapy(2019)

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摘要
•Oral biofilm-dependent diseases can be treated with PACT.•PACT with β-cyclodextrin + methylene blue reduces S. mutans in single species biofilm.•Hydrogen peroxide behaved similarly as photosensitizers.•PACT with laser showed no statistical difference compared to chlorhexidine 0.2%.•The addition of hydrogen peroxide did not enhance the PACT effect.
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关键词
Biofilm,Streptococcus mutans,Photodynamic therapy,Hydrogen peroxide,Antimicrobial photodynamic therapy
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