Organo-nanocatalysis: an Emergent Green Methodology for Construction of Bioactive Oxazines and Thiazines under Ultrasonic Irradiation

A synergistic catalysts system ZnO NPs and Malic acid was used for the highly efficient and eco-friendly synthesis of oxazines and thiazines derivatives. Aldehyde, urea and alkyne derivatives are used as reactants under ultrasonication, which not only allows clean and rapid alteration but also simplifies experimental setup. High yields, environmentally benigness, simple work-up and shorter reaction times are some remarkable advantages of this strategy.