Abstract 19935: MicroRNA-21 Regulates Transforming Growth Factor Beta-1 Release From Platelets: A Novel Mechanism for the Anti-Fibrotic Effects of MicroRNA-21 Inhibition

Temo Barwari,Seda Eminaga,Paul C Armstrong,Melissa V Chan,Ruifang Lu,Javier Barallobre-Barreiro,Xiaoke Yin,Raimund Pechlaner,Sarah R Langley,Anna Zampetaki,Peter Santer,Timothy D Warner,Stefan Kiechl,Johann Willeit,Ajay M Shah,Manuel Mayr

Circulation（2017）

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摘要

Introduction: Fibrosis is a major contributor to cardiac disease. No specific anti-fibrotic therapy is currently available. MicroRNA-21 (miR-21) has been implicated as a regulator of fibrosis with ...

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关键词

MicroRNA, Fibrosis, Blood cells, Extracellular matrix, Proteomics

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