A two-part phase I study to establish and compare the safety and local tolerability of two nasal formulations of XF-73 for decolonization of Staphylococcus aureus: A previously investigated 0.5 mg/g viscosified gel formulation versus a modified formulation.

George A Yendewa,J McLeod Griffiss,Michael R Jacobs,Scott A Fulton,Mary Ann O'Riordan,Wesley A Gray,Howard M Proskin,Peter Winkle,Robert A Salata

Journal of Global Antimicrobial Resistance（2020）

引用 8|浏览11

暂无评分

摘要

•XF-73 led to a rapid reduction in semiquantitative Staphylococcus aureus scores.•Common treatment-related adverse events were rhinorrhoea and nasal dryness.•XF-73 demonstrated safety, tolerability and minimal side effects in healthy volunteers.

查看译文

关键词

Staphylococcus aureus,Decolonisation,XF-73,Antimicrobial resistance

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要